Development of technology for improved production of mammalian
embryos.
Techniques for the in vitro production
(IVP) and monitoring
of mammalian embryos have remained largely unchanged for many years.
In this project, three academic and one
commercial partner will bring
together the approaches of image analysis and metabolic profiling to
establish reliable quality measures for human and porcine embryo production in
vitro. These monitoring techniques will be combined with micro-chamber
technology to make embryo production and monitoring more tractable.
Embryo morphology and timing of development have been associated with
embryo developmental potential but have traditionally been assessed
subjectively. The aim of this work is to use computer assisted image
analysis as a non-invasive, objective and semi-automated approach to
analyse morphological and developmental characteristics indicative
of porcine embryo viability. The research have wide application in
the improvement of embryo-based biotechnologies in domestic animals
and man.
This research work is funded by BBSRC and
Sygen International plc.
    
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Project
sponsors and partnership
